Adjust Font Sizing:

Clinical Trials: How do clinical trial types differ?

April 24th, 2024

Clinical trials are investigational research studies that have various objectives. Our community is benefiting from a great focus on treatment trials that investigate new compounds. The objective is to address unmet needs for people with narcolepsy and idiopathic hypersomnia.

Treatment trials require identifying the endpoints which measure the desired outcome for the trial. This includes using rigorous statistical data to evaluate if a trial is meeting the desired primary endpoint, and meets the safety and efficacy requirement for the potential treatment. The standard subjective measurement for people with narcolepsy and idiopathic hypersomnia include the Epworth Sleepiness Scale (ESS) which evaluates the degree of excessive daytime sleepiness (EDS). More recently, the Idiopathic Hypersomnia Sleepiness Scale (IHSS) has been developed for people with idiopathic hypersomnia to measure the severity of symptoms and burden of disease.

Our community has also benefited from research in narcolepsy for cognitive behavioral therapy interventions. Behavioral trials look at how behaviors may change health outcomes.

Other types of clinical research include screening trials that test ways to identify a specific health disorder. Related to screening are diagnostic trials that look at specific tests that will help with diagnosis. Additionally, quality-of-life trials look at how support and interventions can improve a person’s quality of life.

Learn more about active clinical research.

# # #
Date Created: April 24th, 2024
Last Updated: May 20th, 2024