Orexin nasal spray shows promise as a treatment for narcolepsy
New research shows that an orexin nasal spray holds promise as a treatment for the sleep alterations and EDS that are common symptoms of narcolepsy. Â The study, Â “The effect of intranasal orexin-A (hypocretin-1) on sleep, wakefulness and attention in narcolepsy with cataplexy” appears in the January 2014 online edition of the journalÂ Behavioural Brain Research. Â Researchers in Germany studied 14 people with narcolepsy with cataplexy. Â Subjects received either a nasal spray containing orexin or a placebo. Â Subjects who received the orexin spray had fewer wake-REM sleep transitions and shorter REM phases than those who received the placebo. Â Those who received the spray also preformed better on tests measuring attention.
See the full abstract on theÂ PubMed website.
# # #
Date Created: January 13th, 2014
Last Updated: January 13th, 2014