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New research links histamine to narcolepsy

Two newly published research studies show that histamine-producing neurons in the brain may play a role in narcolepsy.

One study is by Thomas Scammell, MD, professor of Neurology at Beth Israel Deaconess Medical Center in Boston and a member of Narcolepsy Network’s Medical Advisory Board.  It was presented at the 2013 SLEEP meeting in Baltimore. It found that people with narcolepsy have an increased number of neurons that produce histamine.  The study suggests that histamine signaling could be a new way to treat narcolepsy. Read more about Dr. Scammell’s research on the American Academy of Sleep Medicine’s website and on the Science Daily website.

The other study is by Jerome Siegel, PhD, director of the Center for Sleep Research at the UCLA Semel Institute for Neuroscience and Human Behavior and a member of Narcolepsy Network’s Medical Advisory Board. It appears in the online edition of the journal Annals of Neurology.  This study reports that an excess of a type of brain cell containing histamine may be the cause of the loss of hypocretin cells in narcoleptics.  Read more about Dr. Siegel’s research on UCLA’s website and on the Medical Daily website.

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Date Created: July 7th, 2013
Last Updated: July 14th, 2013

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